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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIPK2
All Species:
7.27
Human Site:
S415
Identified Species:
17.78
UniProt:
O43353
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43353
NP_003812.1
540
61195
S415
D
H
K
T
T
P
C
S
S
A
I
I
N
P
L
Chimpanzee
Pan troglodytes
XP_519850
539
61066
S415
H
K
T
T
P
C
S
S
A
I
I
N
P
L
S
Rhesus Macaque
Macaca mulatta
XP_001084563
540
61225
S415
D
H
K
T
T
P
C
S
S
A
T
I
N
P
L
Dog
Lupus familis
XP_535125
538
61029
T415
K
T
T
P
C
A
L
T
V
I
N
P
F
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P58801
539
60382
L415
R
R
A
S
S
C
S
L
A
V
I
S
P
F
L
Rat
Rattus norvegicus
Q9Z2P5
478
52215
G365
T
S
L
T
E
R
R
G
K
E
A
S
F
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511321
791
87316
R410
S
T
T
D
L
H
K
R
K
L
A
E
A
I
T
Chicken
Gallus gallus
NP_001026114
574
63953
S420
L
N
S
L
S
C
Q
S
A
D
E
N
L
S
V
Frog
Xenopus laevis
NP_001080415
720
79835
Q409
D
I
S
A
S
D
L
Q
K
K
K
L
V
D
A
Zebra Danio
Brachydanio rerio
NP_919392
584
65933
V425
E
Y
Q
T
A
Q
V
V
S
D
L
N
I
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.4
86.6
N.A.
84.2
24.8
N.A.
25.6
63.4
25.9
49.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
97.7
90.7
N.A.
89.8
40.9
N.A.
39.7
74.2
44.3
64.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
93.3
0
N.A.
13.3
6.6
N.A.
0
6.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
93.3
6.6
N.A.
33.3
6.6
N.A.
0
33.3
20
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
10
10
0
0
30
20
20
0
10
0
20
% A
% Cys:
0
0
0
0
10
30
20
0
0
0
0
0
0
0
0
% C
% Asp:
30
0
0
10
0
10
0
0
0
20
0
0
0
10
0
% D
% Glu:
10
0
0
0
10
0
0
0
0
10
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
20
10
10
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% G
% His:
10
20
0
0
0
10
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
0
0
0
0
0
0
20
30
20
10
10
0
% I
% Lys:
10
10
20
0
0
0
10
0
30
10
10
0
0
0
0
% K
% Leu:
10
0
10
10
10
0
20
10
0
10
10
10
10
10
30
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
30
20
0
0
% N
% Pro:
0
0
0
10
10
20
0
0
0
0
0
10
20
30
0
% P
% Gln:
0
0
10
0
0
10
10
10
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
10
10
10
0
0
0
0
0
0
0
% R
% Ser:
10
10
20
10
30
0
20
40
30
0
0
20
0
20
10
% S
% Thr:
10
20
30
50
20
0
0
10
0
0
10
0
0
0
10
% T
% Val:
0
0
0
0
0
0
10
10
10
10
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _